Educational Toolbox

Here you will see step by step how is the BIC Guide organized and what functionalities it contains.

Power and sample size estimations are measures of how many patients are needed in a study. Nearly all clinical studies entail studying a sample of patients with a particular characteristic rather than the whole population. We then use this sample to draw inferences about the whole population.

- Jones *et al*.: An introduction to power and sample size estimation

If you want to understand

- power and sample size estimation
- why power is an important part of both study design and analysis
- the differences between sample size calculations in comparative and diagnostic studies and
learn how to perform a sample size calculation

read the article of S R Jones *et al*., An introduction to power and sample size estimation.

More introduction to power can be found from Online Statistics Education and its Power chapter.

A series of educational letters explaining methods to calculate the sample size for various clinical research study designs have been published in the Advanced Journal of Emergency Medicine:

- Sample Size Calculation Guide - Part 1: How to Calculate the Sample Size Based on the Prevalence Rate.
- Sample Size Calculation Guide - Part 2: How to Calculate the Sample Size for an Independent Cohort Study.
- Sample Size Calculation Guide - Part 3: How to Calculate the Sample Size for an Independent Case-control Study.
- Sample Size Calculation Guide - Part 4: How to Calculate the Sample Size for a Diagnostic Test Accuracy Study based on Sensitivity, Specificity, and the Area Under the ROC Curve.

Educational Toolbox

How to use the BIC Guide

24-09-2021

Here you will see step by step how is the BIC Guide organized and what functionalities it contains.

Summary

BIC BRIDGE IVD development pipeline

22-09-2021

Questions to be addressed in the IVD development pipeline.

Summary

Introduction to BIC Tools

22-09-2021

This section provides you with infographics and other visuals which introduce the BIC Tools.